Daniel James has been ruled after suffering a knock.
The 21-year-old has made five appearances and scored three goals for United in the Premier League this year.
The midfielder, who arrived for # 15m in the summer at Old Trafford from Swansea, didn’t train with the group on Wednesday ahead of their Group L conflict.
Ahead of Thursday’s tie, United boss Ole Gunnar Solskjaer affirmed:”Yeah, he (James) got a knock Leicester so he won’t be available.”
Luke Shaw (hamstring), Paul Pogba (foot ) and Anthony Martial (thigh) are also absent before the start of United’s Europa League campaign.
Solskjaer verified that Jesse Lingard and Diogo Dalot have returned to gym and are available for choice.
More to follow…